Assessment of Matrix Metalloproteinases-1 in Septic Acute Respiratory Distress Syndrome: A Report of Two Cases
نویسندگان
چکیده
The extracellular matrix (ECM) does not simply maintain the form of tissues; it is a dynamic factor that plays a major role in cell function. Matrix metalloproteinases (MMPs) are the most important enzymes in ECM degradation, and their activity is controlled strictly by specific inhibitors, that is tissue inhibitors of metalloproteinase (TIMPs). We assessed the clinical course of changes in ECM-degrading enzymes TNF-α, IL-6, IL-8, and nitrite/nitrate (NOx) in the blood of two sep-
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